Towards restoring proper chromosome segregation and preventing ageing

Laura Tovini; Sarah E. McClelland

doi:10.15252/embr.202050322

Towards restoring proper chromosome segregation and preventing ageing

Laura Tovini
, Sarah E. McClelland^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

4 Downloads

Abstract

The natural progressive dysfunction of most living organisms—ageing—has captured the attention of several studies, with the intention to develop rejuvenation strategies. Evidence is emerging of a positive correlation between natural ageing and chromosomal instability (CIN). In this issue of EMBO Reports, Barroso-Vilares et al [1] now show a link between ageing and the erroneous assembly of the apparatus required for a proper cellular division. They compare this mechanism in young and naturally aged human cells and describe a strategy to delay age-related CIN.

Original language	English
Article number	e50322
Pages (from-to)	1-3
Number of pages	3
Journal	EMBO Reports
Volume	21
DOIs	https://doi.org/10.15252/embr.202050322
Publication status	Published - 6 Dec 2020
Externally published	Yes

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AB - The natural progressive dysfunction of most living organisms—ageing—has captured the attention of several studies, with the intention to develop rejuvenation strategies. Evidence is emerging of a positive correlation between natural ageing and chromosomal instability (CIN). In this issue of EMBO Reports, Barroso-Vilares et al [1] now show a link between ageing and the erroneous assembly of the apparatus required for a proper cellular division. They compare this mechanism in young and naturally aged human cells and describe a strategy to delay age-related CIN.

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Towards restoring proper chromosome segregation and preventing ageing

Abstract

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