TY - JOUR
T1 - Translation through collaboration
T2 - practice applied in BAMOS project in in vivo testing of innovative osteochondral scaffolds
AU - Donate, Ricardo
AU - Tamaddon, Maryam
AU - Ribeiro, Viviana
AU - Monzón, Mario
AU - Oliveira, J. Miguel
AU - Liu, Chaozong
N1 - Publisher Copyright:
© 2022, Chinese Medical Multimedia Press Co Ltd. All rights reserved.
PY - 2022/11
Y1 - 2022/11
N2 - Osteoarthritis is the most common chronic degenerative joint disease, recognized by the World Health Organization as a public health problem that affects millions of people worldwide. The project Biomaterials and Additive Manufacturing: Osteochondral Scaffold (BAMOS) innovation applied to osteoarthritis, funded under the frame of the Horizon 2020 Research and Innovation Staff Exchanges (RISE) program, aims to delay or avoid the use of joint replacements by developing novel cost-effective osteochondral scaffold technology for early intervention of osteoarthritis. The multidisciplinary consortium of BAMOS, formed by international leading research centres, collaborates through research and innovation staff exchanges. The project covers all the stages of the development before the clinical trials: design of scaffolds, biomaterials development, processability under additive manufacturing, in vitro test, and in vivo test. This paper reports the translational practice adopted in the project in in vivo assessment of the osteochondral scaffolds developed.
AB - Osteoarthritis is the most common chronic degenerative joint disease, recognized by the World Health Organization as a public health problem that affects millions of people worldwide. The project Biomaterials and Additive Manufacturing: Osteochondral Scaffold (BAMOS) innovation applied to osteoarthritis, funded under the frame of the Horizon 2020 Research and Innovation Staff Exchanges (RISE) program, aims to delay or avoid the use of joint replacements by developing novel cost-effective osteochondral scaffold technology for early intervention of osteoarthritis. The multidisciplinary consortium of BAMOS, formed by international leading research centres, collaborates through research and innovation staff exchanges. The project covers all the stages of the development before the clinical trials: design of scaffolds, biomaterials development, processability under additive manufacturing, in vitro test, and in vivo test. This paper reports the translational practice adopted in the project in in vivo assessment of the osteochondral scaffolds developed.
KW - Bone
KW - Cartilage
KW - In vivo evaluation
KW - Regenerative medicine
KW - Tissue engineering
UR - http://www.scopus.com/inward/record.url?scp=85148861013&partnerID=8YFLogxK
U2 - 10.12336/biomatertransl.2022.02.003
DO - 10.12336/biomatertransl.2022.02.003
M3 - Article
C2 - 36105564
SN - 2096-112X
VL - 3
SP - 102
EP - 104
JO - Biomaterials translational
JF - Biomaterials translational
IS - 2
ER -