Vakzinimmunogene

Adrian Vivian Sinton Hill; Paulo Jorge Gonçalves de Bettencourt; Alexandra Jane Spencer; Nicola Maria Nathalie Ternette; Ahmed Mahmoud Ahmed Ahmed Salman; Caroline Furtado Junqueira; Ricardo Tostes Gazzinelli; Camila Raquel Rodrigues Barbosa

Vakzinimmunogene

Adrian Vivian Sinton Hill (Inventor)
, Paulo Jorge Gonçalves de Bettencourt (Inventor)
, Alexandra Jane Spencer (Inventor)
, Nicola Maria Nathalie Ternette (Inventor)
, Ahmed Mahmoud Ahmed Ahmed Salman (Inventor)
, Caroline Furtado Junqueira (Inventor)
, Ricardo Tostes Gazzinelli (Inventor)
, Camila Raquel Rodrigues Barbosa (Inventor)

Research output: Patent

Abstract

An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80%, 85%, 90%, 95%, 98%, 99% or 100% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided are plasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria.

Original language	English
Patent number	EP4265271A2
IPC	A61K39/015
Priority date	10/05/20
Filing date	11/05/20
Publication status	Published - 25 Oct 2023
Externally published	Yes

Vaccine immunogens
Hill, A. V. S. (Inventor), Bettencourt, P. J. G. (Inventor), Spencer, A. J. (Inventor), Ternette, N. M. N. (Inventor), Salman, A. M. A. A. (Inventor), Junqueira, C. F. (Inventor), Gazzinelli, R. T. (Inventor) & Barbosa, C. R. R. (Inventor), 15 Nov 2023, IPC No. A61K 39/015, European Patent Office, Patent No. EP4275700A2, 11 May 2020, Priority date 10 May 2019, Priority No. GB201906641
Research output: Patent

Cite this

@misc{9b5226d1acdd47a99ace73f15691f341,

title = "Vakzinimmunogene",

abstract = "An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80\%, 85\%, 90\%, 95\%, 98\%, 99\% or 100\% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided are plasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria.",

author = "Hill, \{Adrian Vivian Sinton\} and Bettencourt, \{Paulo Jorge Gon{\c c}alves de\} and Spencer, \{Alexandra Jane\} and Ternette, \{Nicola Maria Nathalie\} and Salman, \{Ahmed Mahmoud Ahmed Ahmed\} and Junqueira, \{Caroline Furtado\} and Gazzinelli, \{Ricardo Tostes\} and Barbosa, \{Camila Raquel Rodrigues\}",

year = "2023",

month = oct,

day = "25",

language = "English",

publisher = "European Patent Office",

address = "Europe",

type = "Patent",

note = "EP4265271A2; A61K39/015",

}

TY - PAT

T1 - Vakzinimmunogene

AU - Hill, Adrian Vivian Sinton

AU - Bettencourt, Paulo Jorge Gonçalves de

AU - Spencer, Alexandra Jane

AU - Ternette, Nicola Maria Nathalie

AU - Salman, Ahmed Mahmoud Ahmed Ahmed

AU - Junqueira, Caroline Furtado

AU - Gazzinelli, Ricardo Tostes

AU - Barbosa, Camila Raquel Rodrigues

PY - 2023/10/25

Y1 - 2023/10/25

N2 - An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80%, 85%, 90%, 95%, 98%, 99% or 100% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided are plasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria.

AB - An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80%, 85%, 90%, 95%, 98%, 99% or 100% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided are plasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria.

M3 - Patent

M1 - EP4265271A2

Y2 - 2020/05/11

PB - European Patent Office

ER -

Vakzinimmunogene

Abstract

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Research output

Vaccine immunogens

Cite this