Innovative response

: how the spinal marrow clot may transform spinal fusion surgery

Abstract

This teaching case discusses a scientific research project developed at IRCCS Istituto Ortopedico Rizzoli. The findings describe the process of creating an innovation in spinal fusion surgery using cell-based therapy based on whole vertebral bone marrow aspirate (vBMA). The purpose is to analyze how this innovation that may impact a significant sector of the medical industry, came into being. And, from this case, we seek to provide insights into how innovation develops and gains diffusion. Given the projected exponential increase of spinal fusions in the next 40 years and high costs of current procedures, vBMA offers an opportunity to transform conventional spinal fusion surgery. In this context, vBMA emerges as a potentially disruptive force, aimed at redefining and revolutionizing conventional spinal fusion surgery practices. It also has the potential to significantly reduce costs while maintaining a high rate in successful patient outcomes, which makes it a game-changer in the medical industry. We discuss the process - from how the idea came about to shifting medical practices and industry resistance - which makes the Case relevant for students of innovatin and enterpreneurship. Students will acquaint themselves with key challenges encountered during the process of innovation adoption and the hurdles associated with bringing about disruptive change.

Date of Award	16 Oct 2023
Original language	English
Awarding Institution	Universidade Católica Portuguesa
Supervisor	Peter V. Rajsingh (Supervisor)