Materiais utilizados para proteção e tratamento de dentes com alterações de estrutura de esmalte
: uma umbrella review

  • Andreia Cristina Gomes (Student)

Student thesis: Master's Thesis


Introduction: Dental enamel can undergo changes at different stages of amelogenesis as a result of the interplay of various factors both at the systemic, environmental and hereditary levels. Consequently, several types of enamel defects such as molar incisor hypomineralization (MIH), hypomineralization of the decidous second molars (HSPM), fluorosis and amelogenesis imperfecta (AI) can arise. Materials and Methods: A systemic umbrella review was performed following the PRISMA guidelines. Results of searches up to April 2022 of the electronic databases Pubmed, Scopus and Web of Science were included in the current study which aimed at attempting to answer the question as to which materials were most suitable for the protection/treatment of permanent molars with enamel alterations, based on the Pico research scientific strategy. After establishing search strategy, studies were selected with defined inclusion and exclusion criteria. The data extracted and calibration was finalized by two independent reviewers. The methodological quality was evaluated by means of the AMSTAR-2 tool and the risk of bias of the systematic review was assessed with the ROBIS tool. For the analysis of the level of evidence, the GRADE tool was utilized. Results: In all, 313 articles were identified during the search of the three databases plus a complementary manual search. After excluding duplicates, 279 articles were evaluated based on their titles and abstracts. Of these, 15 articles were eventually selected for complete reading in order to assess their eligibility. A total of seven studies met the predefined criteria and were deemed suitable for inclusion in the current systematic review. Conclusion: The options currently available for the treatment of teeth with changes in their enamel structure vary from prevention, restoration or even extraction. Although the results of the present study suggest certain treatment options, there is evidently a need for further clinical studies, which might suggest with a higher degree of confidence, which materials are most suitable for the protection/treatment of permanent molars with enamel alterations.
Date of Award15 Jul 2022
Original languagePortuguese
Awarding Institution
  • Universidade Católica Portuguesa
SupervisorAnna Moura (Supervisor), Patrícia Nunes Correia (Co-Supervisor) & Thais Gimenez (Co-Supervisor)


  • Molar-Incisor hypomineralization
  • Treatment
  • Systematic review
  • Amelogenesis imperfecta
  • Developmental dental defect


  • Mestrado em Medicina Dentária

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