Produtos sanguíneos lábeis

: relatório de estágio

Abstract

The Portuguese Blood Institute, IPS, is a competent organization, responsible for managing transfusional medicine nationwide. Its functions include: coordination of all transfusion related activities, from blood donation to blood transfusion; planning the haemovigilance national system, assuring the safety of all blood components available; the guaranty of its continuous services within the national health system, by promoting voluntary blood donation, also with compliance with European and International requirements. IPS is a service structured network divided into three major regional blood centers, located in Porto, Coimbra and Lisbon. The regional blood center in Porto, CRSP, is responsible for blood donation, processing, storage and preservation of whole blood and components in the north region. In CRSP, processing of whole blood into its components (red cells, platelets and plasma) and components storage is assured by the labile blood products laboratory, PSL. This laboratory has the distinctive feature of having developed an automatic whole blood processing system (Atreus 3C). This report is based on the four months internship held in PSL laboratory with the following goals: understanding of the basic principles of blood processing and storage; incorporating the laboratorial routine; understanding blood components distribution management; validation of cryo blood components (fresh frozen plasma and cryoprecipitate) produced in CRSP, complying with European requirements. The main assignments of this internship were participating in whole blood processing with an automatic method, and assessing the quality of cryo blood components and storage and preservation equipment, available in CRSP. This assessment included assays to determine fibrinogen, coagulation factor VIII and cellular concentration in plasma products before and after freezing. It’s reasonable to conclude that this internship had a positive impact. The achievement of the learning goals allowed the understanding of technical skills required in the PSL laboratory daily routine. Moreover, the results for the plasma products evaluation, confirmed the high quality obtained by CRSP methods, even though the storage and preservation equipment doesn’t correspond to the European requirements

Date of Award	2012
Original language	Portuguese
Awarding Institution	Universidade Católica Portuguesa
Supervisor	Salomé Maia (Supervisor) & Elísio Costa (Co-Supervisor)