Bioengineered 3D printed patient-specific meniscus implants

Detalhes do projeto


Knee meniscus lesions are a common injury that can significantly impact an individual's quality of life and socioeconomic status. This project aims to produce 3D printed patient-specific knee meniscus implant has significant clinical relevance, as it has the potential to improve patient outcomes and reduce the burden on the healthcare system by: (1) Improving surgical outcomes; (2) reducing surgical time; (3) improving patient quality of life; (4) reducing healthcare costs; (5) reducing implant revision rates; and (6) reducing recovery time. BeSPECIFIC will develop dual coaxial printing approach with Food and Drug Administration (FDA) and European Medicines Agency (EMA) approved biomaterials, polycaprolactone (PCL), and fibrin, to create customized knee implants. The coaxial printing processes will be optimized using a coaxial setup adapted to the Allevi 2 3D Bioprinter (Allevi by 3D Systems, USA) and further characterized in terms of morphology (e.g., Micro-CT and Scanning Electron Microscope), mechanical performance (e.g., Texture Analyzer), and biological performance (Cytotoxicity tests - ISO 10993-5:2009).
Título curtoBeSPECIFIC
Data de início/fim efetiva6/06/234/06/25

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