A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle

Marta Oliveira; Filipa S. Reis; Diana Sousa; Catarina Tavares; Raquel T. Lima; Isabel C.F.R. Ferreira; Tiago Dos Santos; M. Helena Vasconcelos

doi:10.1039/c4fo00258j

A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle

Marta Oliveira
, Filipa S. Reis
, Diana Sousa
, Catarina Tavares
, Raquel T. Lima
, Isabel C.F.R. Ferreira^*
, Tiago Dos Santos
, M. Helena Vasconcelos

^*Autor correspondente para este trabalho

Resultado de pesquisa › revisão de pares

30 Citações (Scopus)

Resumo

Ganoderma lucidum is one of the most extensively studied mushrooms as a functional food and as a chemopreventive agent due to its recognized medicinal properties. Some G. lucidum extracts have shown promising antitumor potential. In this study, the bioactive properties of various extracts of G. lucidum, from both the fruiting body and the spores, were investigated. The most potent extract identified was the methanolic fruiting body extract, which inhibited the growth of a gastric cancer cell line (AGS) by interfering with cellular autophagy and cell cycle. This journal is

Idioma original	English
Páginas (de-até)	1389-1394
Número de páginas	6
Revista	Food and Function
Volume	5
Número de emissão	7
DOIs	https://doi.org/10.1039/c4fo00258j
Estado da publicação	Publicado - jul. 2014
Publicado externamente	Sim

ODS da ONU

Este resultado contribui para o(s) seguinte(s) Objetivo(s) de Desenvolvimento Sustentável

ODS 3 Boa saúde e bem-estar

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10.1039/c4fo00258j

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Citação

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title = "A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle",

abstract = "Ganoderma lucidum is one of the most extensively studied mushrooms as a functional food and as a chemopreventive agent due to its recognized medicinal properties. Some G. lucidum extracts have shown promising antitumor potential. In this study, the bioactive properties of various extracts of G. lucidum, from both the fruiting body and the spores, were investigated. The most potent extract identified was the methanolic fruiting body extract, which inhibited the growth of a gastric cancer cell line (AGS) by interfering with cellular autophagy and cell cycle. This journal is",

author = "Marta Oliveira and Reis, \{Filipa S.\} and Diana Sousa and Catarina Tavares and Lima, \{Raquel T.\} and Ferreira, \{Isabel C.F.R.\} and \{Dos Santos\}, Tiago and Vasconcelos, \{M. Helena\}",

year = "2014",

month = jul,

doi = "10.1039/c4fo00258j",

language = "English",

volume = "5",

pages = "1389--1394",

journal = "Food and Function",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle

AU - Oliveira, Marta

AU - Reis, Filipa S.

AU - Sousa, Diana

AU - Tavares, Catarina

AU - Lima, Raquel T.

AU - Ferreira, Isabel C.F.R.

AU - Dos Santos, Tiago

AU - Vasconcelos, M. Helena

PY - 2014/7

Y1 - 2014/7

N2 - Ganoderma lucidum is one of the most extensively studied mushrooms as a functional food and as a chemopreventive agent due to its recognized medicinal properties. Some G. lucidum extracts have shown promising antitumor potential. In this study, the bioactive properties of various extracts of G. lucidum, from both the fruiting body and the spores, were investigated. The most potent extract identified was the methanolic fruiting body extract, which inhibited the growth of a gastric cancer cell line (AGS) by interfering with cellular autophagy and cell cycle. This journal is

AB - Ganoderma lucidum is one of the most extensively studied mushrooms as a functional food and as a chemopreventive agent due to its recognized medicinal properties. Some G. lucidum extracts have shown promising antitumor potential. In this study, the bioactive properties of various extracts of G. lucidum, from both the fruiting body and the spores, were investigated. The most potent extract identified was the methanolic fruiting body extract, which inhibited the growth of a gastric cancer cell line (AGS) by interfering with cellular autophagy and cell cycle. This journal is

UR - https://www.scopus.com/pages/publications/84903278799

U2 - 10.1039/c4fo00258j

DO - 10.1039/c4fo00258j

M3 - Article

C2 - 24892846

AN - SCOPUS:84903278799

SN - 2042-6496

VL - 5

SP - 1389

EP - 1394

JO - Food and Function

JF - Food and Function

IS - 7

ER -

A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle

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