TY - GEN
T1 - Analysis of multiple sclerosis DTI images that uses tract based spatial statistics
AU - Oliveira, Joao
AU - Castelo-Branco, Miguel
AU - Morais, Ricardo
AU - Baptista, Sonia
AU - Pereira, Joao
N1 - Publisher Copyright:
© 2015 IEEE.
PY - 2015/4/17
Y1 - 2015/4/17
N2 - Multiple Sclerosis is a demyelinating disease affecting the communication in the central nervous system. Magnetic resonance diffusion imaging provides information about water diffusion in white matter and allows an early detection of abnormalities, comparing to conventional magnetic resonance techniques. The aim of this study is to find out which the brain regions that are damaged during disease progression. Tract-Based Spatial Statistics is a voxelwise multi-subject statistical analysis which performs non-linear registration of each subject's image and projects them onto an alignment-invariant tract representation where the statistical tests are accomplished. This approach improves the sensitivity, objectivity and interpretability of results. The study compares brain images of 64 healthy controls and 59 patients with different stages of Multiple Sclerosis. Some preliminary statistical tests were performed and although the results are still under study, it shows that corticospinal tracts as the most region affected by the disease.
AB - Multiple Sclerosis is a demyelinating disease affecting the communication in the central nervous system. Magnetic resonance diffusion imaging provides information about water diffusion in white matter and allows an early detection of abnormalities, comparing to conventional magnetic resonance techniques. The aim of this study is to find out which the brain regions that are damaged during disease progression. Tract-Based Spatial Statistics is a voxelwise multi-subject statistical analysis which performs non-linear registration of each subject's image and projects them onto an alignment-invariant tract representation where the statistical tests are accomplished. This approach improves the sensitivity, objectivity and interpretability of results. The study compares brain images of 64 healthy controls and 59 patients with different stages of Multiple Sclerosis. Some preliminary statistical tests were performed and although the results are still under study, it shows that corticospinal tracts as the most region affected by the disease.
KW - Diffusion tensor
KW - Multiple sclerosis
KW - Tract-based spatial statistics
UR - https://www.scopus.com/pages/publications/84929258941
U2 - 10.1109/enbeng.2015.7088839
DO - 10.1109/enbeng.2015.7088839
M3 - Conference contribution
AN - SCOPUS:84929258941
T3 - Proceedings - 2015 IEEE 4th Portuguese Meeting on Bioengineering, ENBENG 2015
BT - Proceedings - 2015 IEEE 4th Portuguese Meeting on Bioengineering, ENBENG 2015
A2 - Natal Jorge, Renata M.
A2 - Belinha, Jorge
A2 - Martins, Pedro A. L. S.
A2 - Parente, Marco P. L.
A2 - Leite-Moreira, Adelino
A2 - Tavares, Joao Manuel R. S.
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2015 4th IEEE Portuguese Meeting on Bioengineering, ENBENG 2015
Y2 - 26 February 2015 through 28 February 2015
ER -