Determination of antioxidant capacity using the biological system bacteriophage P22/bacterium Salmonella typhimurium

Maria S. Gião, André B. Borges, Catarina J. Guedes, Tim A. Hogg, Manuela E. Pintado, F. Xavier Malcata

Resultado de pesquisarevisão de pares

7 Citações (Scopus)

Resumo

Bacteriophage/bacterium systems have been employed in the past in assays for virucidal activity. A novel application of one such system is proposed here for the in vivo determination of antioxidant capacity. It was shown that an antioxidant such as gallic acid can effectively protect against oxidative damage brought about by H2O2-but only within a narrow range of concentrations (i.e., from 250 to 500 mg L-1); ascorbic acid, on the other hand, did not exhibit any protective effect against H2O 2. Finally, neither ascorbic nor gallic acid demonstrated a virucidal effect. The P22/Salmonella typhimurium model system thus proved to be useful in the assessment of antioxidant capacity in vivo, at least using those two alternative model antioxidants.

Idioma originalEnglish
Páginas (de-até)22-25
Número de páginas4
RevistaJournal of Agricultural and Food Chemistry
Volume57
Número de emissão1
DOIs
Estado da publicaçãoPublicado - 14 jan. 2009

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