@inproceedings{93b63ea10eda42569750439d172f3908,
title = "Dissimilar symmetric word pairs in the human genome",
abstract = "In this work we explore the dissimilarity between symmetric word pairs, by comparing the inter-word distance distribution of a word to that of its reversed complement. We propose a new measure of dissimilarity between such distributions. Since symmetric pairs with different patterns could point to evolutionary features, we search for the pairs with the most dissimilar behaviour. We focus our study on the complete human genome and its repeat-masked version.",
keywords = "Dissimilarity measure, Human genome, Inter-word distance, Reversed complements",
author = "Tavares, {Ana Helena} and Jakob Raymaekers and Rousseeuw, {Peter J.} and Silva, {Raquel M.} and Bastos, {Carlos A.C.} and Armando Pinho and Paula Brito and Vera Afreixo",
note = "Funding Information: This work was partially supported by the Portuguese Foundation for Science and Technology (FCT), Center for Research & Development in Mathematics and Applications (CIDMA), Institute of Biomedicine (iBiMED) and Institute of Electronics and Informatics Engineering of Aveiro (IEETA), within projects UID/MAT/04106/2013, UID/BIM/04501/2013 and UID/CEC/00127/2013, and by PhD grant PD/BD/105729/2014. The research of P. Brito was financed by the ERDF -European Regional Development Fund through the Operational Programme for Competitiveness and Internationalisation (COMPETE 2020) within project POCI-01-0145-FEDER-006961, and by the FCT as part of project UID/EEA/50014/2013. The research of J. Raymaekers and P. Rousseeuw was supported by projects of Internal Funds KU Leuven. Publisher Copyright: {\textcopyright} Springer International Publishing AG 2017. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.; 11th International Conference on Practical Applications of Computational Biology and Bioinformatics, PACBB 2017 ; Conference date: 21-06-2017 Through 23-06-2017",
year = "2017",
doi = "10.1007/978-3-319-60816-7_30",
language = "English",
isbn = "9783319608150",
series = "Advances in Intelligent Systems and Computing",
publisher = "Springer Verlag",
pages = "248--256",
editor = "Miguel Rocha and {De Paz}, {Juan F.} and Tiago Pinto and Florentino Fdez-Riverola and Mohamad, {Mohd Saberi}",
booktitle = "11th International Conference on Practical Applications of Computational Biology and Bioinformatics, 2017",
address = "Germany",
}