Enantioseparation of chiral pharmaceuticals in biomedical and environmental analyses by liquid chromatography: an overview

Ana R. Ribeiro, Alexandra S. Maia, Quezia B. Cass, Maria E. Tiritan*

*Autor correspondente para este trabalho

Resultado de pesquisarevisão de pares

96 Citações (Scopus)

Resumo

This review aims to present the issues associated to enantioseparation of chiral pharmaceuticals in biological and environmental matrices using chiral stationary phases (CSP). Thus, it related some enantioselective methods in liquid chromatography (LC) and compares the importance given to chiral separation in biomedical and environmental fields. For that the most used CSP, the enantioselective chromatographic methods, their advantages and drawbacks were swiftly revised and compared. The recent advances and the limitations of chiral analytical methods in LC were also discussed.
Idioma originalEnglish
Páginas (de-até)8-21
Número de páginas14
RevistaJournal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
Volume968
DOIs
Estado da publicaçãoPublicado - 15 set. 2014

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