Extending the reservoir of bla IMP-5: the emerging pathogen Acinetobacter bereziniae

Filipa Grosso, Liliana Silva, Clara Sousa, Helena Ramos, Sandra Quinteira, Luísa Peixe*

*Autor correspondente para este trabalho

Resultado de pesquisarevisão de pares

11 Citações (Scopus)

Resumo

Aim: Acinetobacter bereziniae clinical relevance is starting to be recognized; however, very few descriptions of its carbapenem resistance currently exist. Here we characterize two carbapenem-resistant A. bereziniae isolates. Materials & methods: Isolates were obtained from environmental and clinical samples. Carbapenemases were searched by phenotypic, biochemical and PCR assays. Clonality was studied by ApaI-PFGE and genetic location for carbapenemase genes were assessed by I-CeuI and S1 hybridizations. Results: Isolates were not clonally related but both produced the 'exclusively Portuguese' IMP-5, with the clinical isolate also producing an OXA-58. The carbapenemase genes were plasmid located. Conclusion: Our results emphasize the role of non-baumannii Acinetobacter species as important reservoirs of clinically relevant resistance genes that could also contribute to their emergence as nosocomial pathogens.
Idioma originalEnglish
Páginas (de-até)1609-1613
Número de páginas5
RevistaFuture Microbiology
Volume10
Número de emissão10
DOIs
Estado da publicaçãoPublicado - out. 2015
Publicado externamenteSim

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