TY - JOUR
T1 - Functional lipid enriched probiotic cheese
T2 - gastrointestinal stability and potential health benefits
AU - Machado, Manuela
AU - Sousa, Sérgio C.
AU - Rodríguez-Alcalá, Luis M.
AU - Pintado, Manuela
AU - Gomes, Ana Maria
N1 - Funding Information:
This work was supported by National Funds from FCT – Fundação para a Ciência e a Tecnologia through project UIDB/50016/2020. Manuela Machado is grateful for the financial support from FCT through the Doctoral grant reference SFRH/BD/136701/2018.
Publisher Copyright:
© 2023 Elsevier Ltd
PY - 2023/9/1
Y1 - 2023/9/1
N2 - Dairy products are ubiquitous foodstuffs with high consumer acceptance; this facilitates their supplementation with bioactive compounds, such as bioactive lipids. However, their incorporation is limited due to technological challenges and matrix interactions. But what about interactions with probiotics? Thus, this work sought to understand if a probiotic rich cheese fortified with bioactive coconut and avocado oils would be capable of modulating, in vitro, obesity related metabolism. The data showed that, after simulated GIT passage, the oils did not impact the probiotic viable counts and that 50–70% of relevant bioactive fatty acids reached the intestinal phase. Digested fractions also stimulated adipokines production (43–53%), reduced hepatocyte lipidic accumulation (>20%) and increased adipolysis (>50%) and had an anti-inflammatory effect upon macrophages. Based on these results, the proposed solution presented itself as a unique foodstuff capable of being an alternative for the development of a novel line of functional dairy products.
AB - Dairy products are ubiquitous foodstuffs with high consumer acceptance; this facilitates their supplementation with bioactive compounds, such as bioactive lipids. However, their incorporation is limited due to technological challenges and matrix interactions. But what about interactions with probiotics? Thus, this work sought to understand if a probiotic rich cheese fortified with bioactive coconut and avocado oils would be capable of modulating, in vitro, obesity related metabolism. The data showed that, after simulated GIT passage, the oils did not impact the probiotic viable counts and that 50–70% of relevant bioactive fatty acids reached the intestinal phase. Digested fractions also stimulated adipokines production (43–53%), reduced hepatocyte lipidic accumulation (>20%) and increased adipolysis (>50%) and had an anti-inflammatory effect upon macrophages. Based on these results, the proposed solution presented itself as a unique foodstuff capable of being an alternative for the development of a novel line of functional dairy products.
UR - http://www.scopus.com/inward/record.url?scp=85163442884&partnerID=8YFLogxK
U2 - 10.1016/j.idairyj.2023.105700
DO - 10.1016/j.idairyj.2023.105700
M3 - Article
SN - 0958-6946
VL - 144
JO - International Dairy Journal
JF - International Dairy Journal
M1 - 105700
ER -
