Impact of simulated in vitro gastrointestinal digestion on bioactive compounds, bioactivity and cytotoxicity of melon (Cucumis melo L. inodorus) peel juice powder

Ricardo Gómez-García, Ana A. Vilas-Boas, Manuela Machado, Débora A. Campos, Cristóbal N. Aguilar, Ana R. Madureira, Manuela Pintado*

*Autor correspondente para este trabalho

Resultado de pesquisarevisão de pares

Resumo

The objectives of this research work were to evaluate the effect of in vitro gastrointestinal digestion (GIT) on melon peel juice (MPJ) powder from fruit processing industry by-products, considering (i) the recovery and accessibility indexes, (ii) the changes on antioxidant activity, and (iii) the prebiotic effect. Throughout exposition to GIT conditions a decrease on the total phenolic content (TPC = 65.31%) and antioxidant activity by ABTS = 39.77% and DPPH = 45.91% were observed. However, these both parameters exhibited stable accessibility, accounting with 81.89%, 76.55%, and 54.07% for TPC, ABTS and DPPH, respectively. After gastrointestinal digestion, the non-absorbed fraction exhibited a positive impact on the growth of Bifidobacterium and Lactobacillus strains, possibly associated with the high content of simple sugar (glucose and fructose). This fraction also showed to be safe on Caco-2 intestinal cells. These findings suggest that MPJ might be used as a potential food functional ingredient.
Idioma originalEnglish
Número do artigo101726
Número de páginas10
RevistaFood Bioscience
Volume47
DOIs
Estado da publicaçãoPublished - jun 2022

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