TY - JOUR
T1 - Insights into SARS-CoV-2 surveillance among prison populations in Mato Grosso do Sul, Brazil, in 2022
AU - Silva, Liliane Ferreira da
AU - Alcantara, Luiz Carlos Junior
AU - Fonseca, Vagner
AU - Frias, Diego
AU - Zardin, Marina Castilhos Souza Umaki
AU - Lichs, Gislene Garcia de Castro
AU - Esposito, Ana Olivia Pascoto
AU - Xavier, Joilson
AU - Fritsch, Hegger
AU - Lima, Mauricio
AU - Oliveira, Carla de
AU - Arruda, Larissa Domingues Castilho de
AU - Maziero, Livia de Mello Almeida
AU - Barretos, Ellen Caroline Rodrigues
AU - Oshiro, Paulo Eduardo Tsuha
AU - Menezes, Evellyn Fernanda Gimenes Mendes
AU - Cardoso, Lucélia de Freitas
AU - Lemos, Everton Ferreira
AU - Lourenço, José
AU - Albuquerque, Carlos F. C. de
AU - Said, Rodrigo Fabiano do Carmo
AU - Rosewell, Alexander
AU - Demarchi, Luiz Henrique Ferraz
AU - Croda, Julio
AU - Giovanetti, Marta
AU - Gonçalves, Crhistinne Cavalheiro Maymone
N1 - Publisher Copyright:
© 2024 by the authors.
PY - 2024/7/16
Y1 - 2024/7/16
N2 - This study examines the epidemiological and genomic characteristics, along with the transmission dynamics, of SARS-CoV-2 within prison units I and II in Campo Grande, Mato Grosso do Sul, Brazil. Conducted between May and October 2022, it reveals how the virus spreads in the confined settings of prisons, emphasizing the roles of overcrowded cells, frequent transfers, and limited healthcare access. The research involved 1927 participants (83.93% of the total prison population) and utilized nasopharyngeal swabs and RT-qPCR testing for detection. Contact tracing monitored exposure within cells. Out of 2108 samples, 66 positive cases were identified (3.13%), mostly asymptomatic (77.27%), with the majority aged 21–29 and varying vaccination statuses. Next-generation sequencing generated 28 whole genome sequences, identifying the Omicron variant (subtypes BA.2 and BA.5) with 99% average coverage. Additionally, the study seeks to determine the relationship between immunization levels and the incidence of SARS-CoV-2 cases within this enclosed population. The findings underscore the necessity of comprehensive control strategies in prisons, including rigorous screening, isolation protocols, vaccination, epidemiological monitoring, and genomic surveillance to mitigate disease transmission and protect both the incarcerated population and the broader community.
AB - This study examines the epidemiological and genomic characteristics, along with the transmission dynamics, of SARS-CoV-2 within prison units I and II in Campo Grande, Mato Grosso do Sul, Brazil. Conducted between May and October 2022, it reveals how the virus spreads in the confined settings of prisons, emphasizing the roles of overcrowded cells, frequent transfers, and limited healthcare access. The research involved 1927 participants (83.93% of the total prison population) and utilized nasopharyngeal swabs and RT-qPCR testing for detection. Contact tracing monitored exposure within cells. Out of 2108 samples, 66 positive cases were identified (3.13%), mostly asymptomatic (77.27%), with the majority aged 21–29 and varying vaccination statuses. Next-generation sequencing generated 28 whole genome sequences, identifying the Omicron variant (subtypes BA.2 and BA.5) with 99% average coverage. Additionally, the study seeks to determine the relationship between immunization levels and the incidence of SARS-CoV-2 cases within this enclosed population. The findings underscore the necessity of comprehensive control strategies in prisons, including rigorous screening, isolation protocols, vaccination, epidemiological monitoring, and genomic surveillance to mitigate disease transmission and protect both the incarcerated population and the broader community.
KW - COVID-19
KW - Epidemiological monitoring
KW - Genomic monitoring
KW - Prison
KW - SARS-CoV-2
UR - http://www.scopus.com/inward/record.url?scp=85199643027&partnerID=8YFLogxK
U2 - 10.3390/v16071143
DO - 10.3390/v16071143
M3 - Article
C2 - 39066305
AN - SCOPUS:85199643027
SN - 1999-4915
VL - 16
JO - Viruses
JF - Viruses
IS - 7
M1 - 1143
ER -