@article{2c9d334581ed4d9b87cdfc4e2b79a8b9,
title = "Paving the way: contributions of big data to apicomplexan and kinetoplastid research",
abstract = "In the age of big data an important question is how to ensure we make the most out of the resources we generate. In this review, we discuss the major methods used in Apicomplexan and Kinetoplastid research to produce big datasets and advance our understanding of Plasmodium, Toxoplasma, Cryptosporidium, Trypanosoma and Leishmania biology. We debate the benefits and limitations of the current technologies, and propose future advancements that may be key to improving our use of these techniques. Finally, we consider the difficulties the field faces when trying to make the most of the abundance of data that has already been, and will continue to be, generated.",
keywords = "Apicomplexa, Functional screens, Genomics, Kinetoplastid, Microscopy, Proteomics, Transcriptomics",
author = "Kent, {Robyn S.} and Briggs, {Emma M.} and Colon, {Beatrice L.} and Catalina Alvarez and Pereira, {Sara Silva} and {De Niz}, Mariana",
note = "Funding Information: We thank both reviewers whose comments improved our work. We thank also our various funders: RSK is funded by the American Heart Association Postdoctoral Fellowship (grant no. 20POST35220017) and U.S. Public Health Service (grant no. AI 139201). EMB is funded by the Wellcome Trust (grant no. 218648/Z/19/Z). SSP is funded by Marie Sk{\l}odowska-Curie Individual Standard European Fellowship (grant no. 839960) and Funda{\c c}{\~a}o Bial (Project 7/2021). MDN is funded by Human Frontier Science Individual Fellowship (grant LT000047/2019-L). Publisher Copyright: Copyright {\textcopyright} 2022 Kent, Briggs, Colon, Alvarez, Silva Pereira and De Niz.",
year = "2022",
month = jun,
day = "6",
doi = "10.3389/fcimb.2022.900878",
language = "English",
volume = "12",
journal = "Frontiers in Cellular and Infection Microbiology",
issn = "2235-2988",
publisher = "Frontiers Media S.A.",
}