Peptide-rich extracts from spent yeast waste streams as a source of bioactive compounds for the nutraceutical market

Ana Sofia Oliveira, Joana Odila Pereira*, Carlos Ferreira, Margarida Faustino, Joana Durão, Manuela E. Pintado, Ana P. Carvalho

*Autor correspondente para este trabalho

Resultado de pesquisarevisão de pares

15 Citações (Scopus)

Resumo

Spent yeast is one of the main fermentation process by-products and several bioactive ingredients have been extracted from it, such as mannans and β-glucans. These extraction processes generate waste streams rich in protein, that can still be used to produce peptide-rich extracts. This work describes the use of a scalable and low-cost process to obtain yeast peptide extracts in a circular economy concept. Peptide fractions produced contained 48.3 to 86.4% of protein (w/w) and essential amino acids amounts higher than those defined by FAO and WHO references. Regarding their bioactive properties, extracts exhibited strong antihypertensive and antioxidant activities. Furthermore, an inhibition of 62.0–71.3% in HMG-CoA reductase was observed, a feature hereby described for the first time, thus stating the cholesterol-lowering capacity of yeast peptides. In conclusion, due to their combined nutritional and bioactive characteristics, the produced yeast peptide extracts are good candidates for dietary supplementation and functional foods.
Idioma originalEnglish
Número do artigo103148
Número de páginas10
RevistaInnovative Food Science and Emerging Technologies
Volume81
DOIs
Estado da publicaçãoPublicado - out. 2022

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