TY - JOUR
T1 - Plant extracts and SARS-CoV-2
T2 - research and applications
AU - Heleno, Sandrina A.
AU - Carocho, Marcio
AU - Reis, Filipa S.
AU - Pires, Tânia C. S. P.
AU - Pintado, Manuela
AU - Ferreira, Isabel C. F. R.
AU - Barros, Lillian
N1 - Funding Information:
This research was funded by the Portuguese Fundação para Ciência e Tecnologia (FCT), which financed the Centro de Investigação de Montanha through (UIDB/00690/2020), as well as the researchers S. Heleno and M. Carocho (CEECIND/00831/2018, CEECIND/03040/2017) as well as L. Barros. The research was also funded by the Programa Operacional Regional Norte 2020, within the “PlantCovid” project, NORTE-01-02B7-FEDER-054870.
Funding Information:
The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES to the CIMO (UIDB/00690/2020). Acknowledgments to the European Fund for Regional Development through the Programa Operacional Regional Norte 2020, within the “PlantCovid” project, NORTE-01-02B7-FEDER-054870. S. Heleno and M. Carocho thank FCT for their individual employment program-contract (CEECIND/00831/2018, CEECIND/03040/2017). L. Barros also thanks the national funding by FCT, through the institutional scientific employment program-contract for her contract.
Publisher Copyright:
© 2023 by the authors.
PY - 2023/1/31
Y1 - 2023/1/31
N2 - The recent pandemic of COVID-19 caused by the SARS-CoV-2 virus has brought upon the world an unprecedented challenge. During its acute dissemination, a rush for vaccines started, making the scientific community come together and contribute to the development of efficient therapeutic agents and vaccines. Natural products have been used as sources of individual molecules and extracts capable of inhibiting/neutralizing several microorganisms, including viruses. Natural extracts have shown effective results against the coronavirus family, when first tested in the outbreak of SARS-CoV-1, back in 2002. In this review, the relationship between natural extracts and SARS-CoV is discussed, while also providing insight into misinformation regarding the use of plants as possible therapeutic agents. Studies with plant extracts on coronaviruses are presented, as well as the main inhibition assays and trends for the future regarding the yet unknown long-lasting effects post-infection with SARS-CoV-2.
AB - The recent pandemic of COVID-19 caused by the SARS-CoV-2 virus has brought upon the world an unprecedented challenge. During its acute dissemination, a rush for vaccines started, making the scientific community come together and contribute to the development of efficient therapeutic agents and vaccines. Natural products have been used as sources of individual molecules and extracts capable of inhibiting/neutralizing several microorganisms, including viruses. Natural extracts have shown effective results against the coronavirus family, when first tested in the outbreak of SARS-CoV-1, back in 2002. In this review, the relationship between natural extracts and SARS-CoV is discussed, while also providing insight into misinformation regarding the use of plants as possible therapeutic agents. Studies with plant extracts on coronaviruses are presented, as well as the main inhibition assays and trends for the future regarding the yet unknown long-lasting effects post-infection with SARS-CoV-2.
KW - Anti-viral agents
KW - COVID-19
KW - Pandemic
KW - SARS-CoV-2
KW - Secondary metabolism
UR - http://www.scopus.com/inward/record.url?scp=85149238214&partnerID=8YFLogxK
U2 - 10.3390/life13020386
DO - 10.3390/life13020386
M3 - Review article
C2 - 36836744
AN - SCOPUS:85149238214
SN - 2075-1729
VL - 13
JO - Life
JF - Life
IS - 2
M1 - 386
ER -
