The disease burden of heart failure in Portugal

G. Jesus, R. Fiorentino, R. Ascenção, M. Gouveia, J. Costa, P. Broeiro, C. Fonseca, M. Borges

Resultado de pesquisarevisão de pares

1 Transferências (Pure)


Objectives: The objective of this study is to estimate the disease burden of Heart Failure (HF) in Portugal for 2014.MethOds: The HF burden was measured in Disability Adjusted Life Years (DALY) resulting from the sum of Years Lost due to Disability (YLD) and Years of Life Lost (YLL) due to premature death. YLL were esti-mated based on the mortality rates reported by the European Detailed Mortality Database. For YLD, the three disability weights (mild moderate and severe) presented by the Global Burden of Disease Study (2015) were considered. Patients in the first class of the New York Heart Association (NYHA) Functional Classification, where considered to have no disability associated to HF. The average total disease duration by age group and the overall incidence were estimated using the software DisMod II, calibrated with the prevalence of NYHA class II-IV, relative risk of mortality and a remission rate of zero. Prevalence was estimated using the microdata of a previously conducted national community-based epidemiological survey while relative risk of mortality came from the international literature. It was assumed that incidence by severity class followed the same pattern as prevalence and that duration was independent from severity.Results: In 2014, HF incident cases in NYHA class II-IV were estimated to be 38,960 (394.74/100,000 inhabitants). The deaths for HF patients amounted to 4,688, 4.7% of overall deaths, with women being responsible for 66.7% of HF mortality. Overall, DALY totaled 21,162, with 53.8% due to YLL and 46.2% due to YLD. Women contributed to most of the overall disease burden in terms of DALY (57.0%) with YLL and YLD estimated at 6.944 and 5.118, respectively.cOnclusiOns:Heart Failure is an important cause of disease burden in Portugal. Heart Failure should be an important target for health policy interventions.
Idioma originalEnglish
Número do artigoPCV161
Páginas (de-até)A630-A630
Número de páginas1
RevistaValue in Health
Número de emissão9
Estado da publicaçãoPublicado - 2017

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