In this chapter, we explore how cognitive reserve is implicated in coping with the negative consequences of brain pathology and age-related cognitive decline. Individual differences in cognitive performance are based on different brain mechanisms (neural reserve and neural compensation), and reflect, among others, the effect of education, occupational attainment, leisure activities, and social involvement. These cognitive reserve proxies have been extensively associated with efficient executive functioning. We discuss and focus particularly on the compensation mechanisms related to the frontal lobe and its protective role, in maintaining cognitive performance in old age or even mitigating the clinical expression of dementia.
Idioma originalEnglish
Título da publicação do anfitriãoNeurophysiology - networks, plasticity, pathophysiology and behavior
EditoresThomas Heinbockel
Número de páginas19
ISBN (eletrónico)9781803560700
ISBN (impresso)9781803560687, 9781803560694
Estado da publicaçãoPublicado - 21 dez. 2022

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